Synthesis of Surfactants Derived from 2-Mercaptobenzimidazole and Study of Their Acute Toxicity and Analgesic and Psychotropic Activities

Table 2

Effect of 2-mercaptobenzimidazole 1 and derivatives 2–5 on acetic acid-induced cramps in mice.

Products	Doses (mg/kg)	Number of cramps in 10 min	Percentage of inhibition (%)
1	200	26.20 ± 3.96	33.67 ± 10.03
2	200	25.00 ± 3.53	36.70 ± 08.95
3	200	19.60 ± 3.78	50.37 ± 09.57
4	200	17.60 ± 4.82	55.44 ± 12.22
5	200	19.75 ± 4.24	50.00 ± 10.81
Acetylsalicylic acid	100	09.60 ± 1.50	75.69 ± 03.79
Control	—	39.50 ± 2.60	—

; compared to control.