Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases

Figure 5

Evaluation of the apoptosis induced by the three N,N-disubstituted Schiff bases on two leukemia cell lines (a) and two prostate cell lines (b) using the annexin V-FITC/IP staining, followed by flow cytometer analysis. (c) Comparison of the apoptosis induced by compounds 1a, 1b, and 1c. Histograms represent annexin V-FITC/IP stained cells cultured in the presence of 5 μmol/L of tested compounds. Data showed the percentage of late induced apoptotic cells (upper right quadrant) and represent the mean ± standard deviation of three independent experiments, each performed in duplicate. ; .

(a)

(b)

(c)