Research Article

Collagen Content in Skin and Internal Organs of the Tight Skin Mouse: An Animal Model of Scleroderma

Table 2

Hydroxyproline content in lung, heart, and kidney of B6 +/+ and B6 Tsk/+ mice.

GenotypeSexAge in weeksNumber of miceLung
Mean ± S.E
Heart
Mean ± S.E
Kidney (L)
Mean ± S.E
Kidney (R)
Mean ± S.E

B6 +/+F24–275
B6 Tsk/+F23–256

B6 +/+M24–276
B6 Tsk/+M24–276

Hydroxyproline is expressed as g/per organ content in lung, heart, and kidney. F: females; M: males. L: left; R: right. S.E: standard error. Statistical analysis was performed using -test following analysis of variance.