Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics
Figure 7
Comparison of XB recruitment dynamic, , in detergent-skinned fibers reconstituted with , or . was estimated by fitting the R-D model to the force responses from muscle fibers to chirp-length perturbations [35]. One-way ANOVA was used to compare estimates of in and fibers with the data from cTnCWT fibers as controls. Values are expressed as mean SEM. Number of fibers tested in each group is as follows: cTnCWT, ; , ; , . Minimal statistical significance was set at . *; **