Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model

Figure 4

RGS5-expressing ovarian tumors increase the number of CD31-positive vessel-like structures. Tumor specimens were sectioned and prepared on slides for immunofluorescence. (a) Tumor sections were imaged for CD31 expression (red, 20x magnification). (b) CD31-positive vasculature was quantified from compiled whole tumor images (𝑁=4 vector, 𝑁=4 RGS5) using CellSens and GraphPad Prism software. **𝑃<0.01, comparing vector versus RGS5.

(a)

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