Long-Term Voluntary Physical Exercise Exerts Neuroprotective Effects and Motor Disturbance Alleviation in a Rat Model of Parkinson’s Disease

Figure 4

Effects of long-term exercise on locomotor activity and anxiety-like behavior, evaluated using the open-field test. (a) Representative traces of rat movement during the open-field test in the sham and exercise-treated rats at prelesion, 4 weeks postlesion, and 8 weeks postlesion. No significant differences were observed between the exercise and nonexercise groups in overall traveled distance (b) and time in the center (c) during the observation time points.

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