Research Article

Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model

Table 3

Effect of sevoflurane on latency and error times in the step-down latency test of mice ().

GroupsTimeBaseline timeTest period time
Latency (s, )Number of errors (times, domain 0)Latency (s, )Number of errors (times, domain 0)

SevofluraneT1180.5 (100.2)1.0 (1.0)37.5 (66.0)ab3.0 (3.5)ab
T2211.5 (79.5)1.5 (1.0)153.5 (168.5)1.5 (2.8)
T3274.0 (53.8)1.0 (1.0)297.5 (47.0)1.0 (0.0)
T4262.0 (104.8)l.0 (l.0)290.0 (105.0)1.0 (0.0)
ControlT1253.5 (105.8)1.5 (1.8)164.0 (136.5)1.0 (1.0)
T2253.0 (63.5)1.0 (0.8)173.0 (265.0)1.0 (1.5)
T3260.5 (78.8)1.5 (1.0)294.5 (102.0)1.0 (0.0)
T4254.0 (97.0)1.0 (1.0)296.0 (9.75)1.0 (0.8)

Note: avs. the control group and bvs. the baseline time.