Research Article
Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model
Table 3
Effect of sevoflurane on latency and error times in the step-down latency test of mice (
).
| Groups | Time | Baseline time | Test period time | Latency (s, ) | Number of errors (times, domain 0) | Latency (s, ) | Number of errors (times, domain 0) |
| Sevoflurane | T1 | 180.5 (100.2) | 1.0 (1.0) | 37.5 (66.0)ab | 3.0 (3.5)ab | T2 | 211.5 (79.5) | 1.5 (1.0) | 153.5 (168.5) | 1.5 (2.8) | T3 | 274.0 (53.8) | 1.0 (1.0) | 297.5 (47.0) | 1.0 (0.0) | T4 | 262.0 (104.8) | l.0 (l.0) | 290.0 (105.0) | 1.0 (0.0) | Control | T1 | 253.5 (105.8) | 1.5 (1.8) | 164.0 (136.5) | 1.0 (1.0) | T2 | 253.0 (63.5) | 1.0 (0.8) | 173.0 (265.0) | 1.0 (1.5) | T3 | 260.5 (78.8) | 1.5 (1.0) | 294.5 (102.0) | 1.0 (0.0) | T4 | 254.0 (97.0) | 1.0 (1.0) | 296.0 (9.75) | 1.0 (0.8) |
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Note: avs. the control group and bvs. the baseline time. |