Efficacy of a Computer-Assisted Cognitive Rehabilitation Intervention in Relapsing-Remitting Multiple Sclerosis Patients: A Multicenter Randomized Controlled Trial
Table 3
Performance on neuropsychological measures for the RehaCom and control group at baseline, posttreatment, and at 6-month follow-up.
MS RehaCom group () Mean (95% CI)
SD
MS control group () Mean (95% CI)
SD
SRTLTS
T0
36.72 (34.57–38.86)
5.94
36.42 (34.37–38.48)
5.08
T1
43.47 (40.55–46.39)
8.09
36.38 (34.34–38.43)
5.06
T2
43.00 (40.04–45.96)
8.21
—
—
SRTDR
T0
6.09 (5.44–6.75)
1.82
7.15 (6.65–7.66)
1.25
T1
8.22 (7.59–8.85)
1.75
7.12 (6.73–7.50)
7.12
T2
7.75 (7.11–8.39)
1.77
—
—
BVMT-RT
T0
21.40 (17.10–24.30)
5.85
22.50 (17.80–25.20)
7.80
T1
24.50 (19.50–26.30)
6.02
20.80 (17.50–24.60)
6.85
T2
23.10 (18.90–25.20)
6.40
—
—
VFT phon
T0
31.88 (28.92–34.83)
8.20
29.81 (23.39–30.23)
8.46
T1
33.13 (30.60–35.65)
7.01
29.95 (24.16–30.53)
7.88
T2
31.47 (29.20–33.74)
6.29
—
—
VFT sem
T0
41.03 (38.09–43.97)
8.16
40.50 (36.69–44.31)
9.44
T1
43.56 (40.55–46.57)
8.34
39.58 (35.60–43.55)
9.83
T2
42.06 (39.05–45.08)
8.35
—
—
SDMT
T0
36.91 (33.89–39.92)
8.36
37.42 (33.03–41.82)
10.87
T1
40.03 (37.48–42.58)
7.08
37.43 (33.44–41.40)
9.85
T2
37.50 (35.25–39.75)
6.25
—
—
TMT-A
T0
73.50 (65.08–81.92)
23.35
69.27 (52.05–68.48)
20.30
T1
59.53 (52.86–66.20)
18.49
68.88 (52.67–69.10)
20.32
T2
60.31 (53.28–67.34)
19.49
—
—
TMT-B
T0
145. 81 (129.12–162.50)
46.29
111. 54 (96.23–126.84)
37.89
T1
113.28 (94.72–131.84)
51.47
110.96 (96.18–125.75)
36.60
T2
115.78 (97.40–134.16)
50.98
—
—
SNST
T0
59.80 (53.30–64.50)
15.50
58.70 (52.60–63.80)
17.30
T1
63.50 (57.40–68.10)
13.25
57.60 (52.90–62.70)
14.20
T2
62.10 (56.90–66.20)
14.20
—
—
Notes: All values are raw scores. T0: baseline assessment; T1: posttreatment assessment; T2: 6-month follow-up assessment. MS control group was not assessed at 6-month follow-up. SRTLTS: Selective Reminding Test Long-Term Storage; SRTDR: Selective Reminding Test-Delayed Recall; BVMT-RT: Brief Visuospatial Memory Test-Revised Total Recall; VFT phon: Greek Verbal Fluency Test-Phonemic Fluency; VFT sem: Greek Verbal Fluency Test-Semantic Fluency; SDMT: Symbol Digit Modalities Test; TMT-A and TMT-B: Greek Trail Making Test Part A, Greek Trail Making Test Part B; SNST: Stroop Neuropsychological Screening Test.
