BioMed Research International

Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models


Publishing date
19 Sep 2014
Status
Published
Submission deadline
02 May 2014

1INSERM UMR1121 “Biomaterials and Bioengineering,” Strasbourg, France

2Middle East Technical University, Ankara, Turkey

3Dublin City University, Dublin, Ireland


Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models

Description

The current generation of engineered tissues has resulted in successful clinical applications in trachea, skin, and cartilage. For the engineering of more intricate tissues, however, it is still necessary to attain more precise control of cellular microenvironment. Guiding local differentiation of stem cells from various resources seeded in biomaterials and also exerting precise control over the phenotype of different cell types simultaneously are essential for engineering complex, multicellular tissues. Moreover, the use of tissue-engineered products as disease or test tissue models, as fundamental research tools and materials for pharmaceutical testing, further increases the need to understand and mimic the multicellular 3D microenvironments in tissues. These advancements also bring out the need to develop efficient methods to monitor and quantify the changes within the engineered tissues both in vitro and in vivo. Studies that improve the understanding of the cell microenvironment for different tissue settings would help us produce more robust and functional engineered tissues.

We invite investigators to contribute original research and review articles that focus on design, modification, and utilization of microenvironments for tissue engineering and regenerative medicine purposes and who apply novel techniques to monitor and characterize engineered tissues in vitro and in vivo. We are particularly interested in studies that employ biochemical, biophysical, and topographical cues for directing cell behavior within 3D settings. Potential topics include, but are not limited to:

  • Novel in vitro and in vivo engineered tissue monitoring techniques and use of biosensors in tissue engineering applications
  • Techniques and applications of 3D cell microenvironment design, particularly for stem cells
  • Stimuli-responsive and hybrid biomaterials for development of 3D complex cell microenvironments
  • Role of nano/microscale surface topography and surface modifications on cell guidance, differentiation, and phenotype in engineered tissues
  • Modular tissue engineering methods and other fabrication techniques for the creation of gradients of microenvironments for artificial tissues
  • Biomaterial based coculture systems and heterotypic cell-cell interaction control via designed microenvironments
  • Incorporation of drug, cytokine, and morphogen-controlled delivery systems within engineered tissues

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/tissue.engineering/ctm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 951626
  • - Editorial

Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models

Nihal Engin Vrana | Vasif Hasirci | ... | Albana Ndreu-Halili
  • Special Issue
  • - Volume 2014
  • - Article ID 921905
  • - Review Article

Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances

Julien Barthes | Hayriye Özçelik | ... | Nihal Engin Vrana
  • Special Issue
  • - Volume 2014
  • - Article ID 648459
  • - Review Article

The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes

Yue Gao | Shuyun Liu | ... | Quanyi Guo
  • Special Issue
  • - Volume 2014
  • - Article ID 760709
  • - Clinical Study

The Effect of Autologous Activated Platelet Rich Plasma (AA-PRP) Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

V. Cervelli | S. Garcovich | ... | P. Gentile
  • Special Issue
  • - Volume 2014
  • - Article ID 762570
  • - Research Article

The Study of the Frequency Effect of Dynamic Compressive Loading on Primary Articular Chondrocyte Functions Using a Microcell Culture System

Wan-Ying Lin | Yu-Han Chang | ... | Min-Hsien Wu
  • Special Issue
  • - Volume 2014
  • - Article ID 209469
  • - Research Article

Characterization of Silk Fibroin Modified Surface: A Proteomic View of Cellular Response Proteins Induced by Biomaterials

Ming-Hui Yang | Shyng-Shiou Yuan | ... | Yu-Chang Tyan
BioMed Research International
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Acceptance rate8%
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