TY - JOUR A2 - Lehto, Vesa-Pekka AU - Loskutova, Ksenia AU - Grishenkov, Dmitry AU - Ghorbani, Morteza PY - 2019 DA - 2019/07/14 TI - Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics SP - 9480193 VL - 2019 AB - Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase transition to gas after exposure to a pressure amplitude above a certain threshold. In recent years, new techniques in ultrasound diagnostics and therapeutics have been developed which utilize microformulations with various physical and chemical properties. The purpose of this review is to give the reader a general idea on how ADV can be implemented for the existing biomedical applications of droplet vaporization. In this regard, the recent developments in ultrasound therapy which shed light on the ADV are considered. Modern designs of capsules and nanodroplets (NDs) are shown, and the material choices and their implications for function are discussed. The influence of the physical properties of the induced acoustic field, the surrounding medium, and thermophysical effects on the vaporization are presented. Lastly, current challenges and potential future applications towards the implementation of the therapeutic droplets are discussed. SN - 2314-6133 UR - https://doi.org/10.1155/2019/9480193 DO - 10.1155/2019/9480193 JF - BioMed Research International PB - Hindawi KW - ER -