Epigenetic Modifications in Placenta are Associated with the Child’s Sensitization to Allergens
Table 3
(a) Histopathology of the 171 placentas available from the participating 173 mothers
Lifestyle
Anthroposophic N = 24
Partly anthroposophic N = 105
Anthroposophic and partly anthroposophic N = 129
Non-anthroposophic N = 42
Placenta histopathology, n/N (%)
Chorioamnionitis
9/24 (37.5%)
44/104 (42.3%)
53/128 (42.4%)
20/42 (47.6%)
0.59
Vasculitis chorion plate
1/24 (4.2%)
15/104 (14.4%)
16/128 (12.5%)
7/42 (16.7%)
0.60
Vasculitis umbilical cord
2/24 (8.3%)
9/103 (8.6%)
11/127 (8.5%)
2/42 (4.8%)
0.73
Funisitis
1/24 (4.2%)
3/103 (2.9%)
4/127 (3.1%)
1/42 (2.4%)
1.00
Villitis
4/24 (16.7%)
20/105 (19%)
24/129 (18.6%)
4/42 (9.5%)
0.23
p for comparisons of the combined anthroposophic and partly anthroposophic versus the nonanthroposophic lifestyle group by Fisher’s exact test.
(b) Sensitization during childhood in relation to placenta histopathology among families with any data both from placenta and child blood sample available (N=155).
Children sensitized to food allergens and/or aeroallergens, n/N
