Antibody-Mediated Osseous Regeneration for Bone Tissue Engineering in Canine Segmental Defects

Figure 2

CT scan images of the bone formation within canine segmental defects. Three-dimensional images of the defects after 6 weeks in isotype mAb (a1), rhBMP-2 (b1), and anti-BMP-2 (c1) groups. Coronal sections of the defect’s center slide were shown at 6th week in isotype mAb (a2), rhBMP-2 (b2), and anti-BMP-2 mAb (c2) groups. Same sections at 12th week in isotype mAb (a3), rhBMP-2 (b3), and anti-BMP-2 (c3) groups.