Antimicrobial Potential of Caffeic Acid against Staphylococcus aureus Clinical Strains
Table 1
Antibiotic resistance profiles for tested Staphylococcus aureus strains.
Strain
Cefoxitin Diameter of the Inhibition Zone [mm]
Methicillin resistance according to mecA presence
Erythromycin Diameter of the Inhibition Zone [mm]
Clindamycin Diameter of the Inhibition Zone [mm]
Mechanism of Resistance to ML Antibiotics
The MIC of Vancomycin μg/mL
Vancomycin resistance profile
S. aureus ATCC 25923
35
MSS
25
25
-
0.75
S. aureus ATCC 43300
21
MRS
0
0
cML
0.38
S
S. aureus ATCC 6538
31
MRSA
30
30
-
0.50
S
S. aureus
34
MSSA
25
25
-
0.75
S
S. aureus 2
32
MSSA
23
25
-
0.38
S
S. aureus 3
31
MSSA
0
25
iML
0.50
S
S. aureus 4
32
MRSA
25
27
-
0.50
S
S. aureus 5
13
MRSA
0
30
iML
0.75
S
S. aureus 6
31
MSSA
30
35
-
0.38
S
S. aureus 7
32
MRSA
35
33
-
0.50
S
S. aureus 8
31
MSSA
30
35
-
0.38
S
S. aureus 9
30
MRSA
35
25
-
0.38
S
S. aureus 10
31
MSSA
10
22
iML
0.38
S
S. aureus 11
31
MSSA
21
22
-
0.38
S
S. aureus 12
8
MRSA
0
0
cML
0.75
S
S. aureus 13
14
MRSA
0
0
cML
0.75
S
S. aureus 14
0
MRSA
0
0
cML
0.75
S
S. aureus 15
21
MRSA
25
30
-
0.38
S
S. aureus 16
18
MRSA
0
0
cML
0.50
S
S. aureus 17
11
MRSA
0
0
cML
0.38
S
S. aureus 18
19
MRSA
25
30
-
0.50
S
S. aureus 19
14
MRSA
0
0
cML
0.50
S
S. aureus 20
19
MRSA
0
0
cML
0.38
S
taphylococcus aureus 1 ÷ 20: strains from intractable surgical wounds. SSA: methicillin-susceptible S. aureus. RSA: methicillin-resistant S. aureus. ML: constitutive macrolide, lincosamide, and type B streptogramin mechanism. ML: inducible macrolide, lincosamide, and type B streptogramin mechanism. : sensitive.