Research Article

Resveratrol Increases Serum BDNF Concentrations and Reduces Vascular Smooth Muscle Cells Contractility via a NOS-3-Independent Mechanism

Table 1

Maximal relative response for phenylephrine in relation to the absence and presence of L-NAME in resveratrol treated and control groups.

[%]2

Control, PHE (10 μM/L)898.0 ± 3.3
Resveratrol pretreated rats, PHE (10 μM/L)1682.0 ± 2.0p < 0.001
Control (PHE) 10 μM/L + L-NAME (10−5 M/L)898.0 ± 3.0
Resveratrol pretreated rats + L-NAME (10−5 M/L)1299.0 ± 4.0p = ns

Number of concentration-response curves used for calculations. : calculated as a percent of maximal response for PHE; value calculated versus controls; value calculated versus control (PHE) 10 μM/L + L-NAME. PHE: phenylephrine.