Research Article

Identification and Characterization of a Splicing Variant in the 5′ UTR of the Human TLR5 Gene

Figure 1

The exon structure of the human TLR5 gene and detection of TLR5 splice variants in human monocytic THP-1 cell line. (a) Human TLR5 contains seven exons (depicted as boxes). Exons IV+ are alternative (marked by shading). (b) PCR was performed with primers designed to exons I and VI (dotted arrows), or (c) exon IV and exon V (solid arrows). The amplified products were visualized by gel electrophoresis. IV+ designates the newly discovered exon.
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