Research Article
Abnormal Biomarkers of Homocysteine Metabolism in Neonates with Conotruncal Heart Defects
Table 2
Total homocysteine (tHcy), folate, and cobalamin levels in umbilical cord blood and mothers’ venous blood samples in all investigated groups.
| | Variable | Conotruncal heart defects
() | Nonconotruncal heart defects
() | Controls
() | p value |
| | Umbilical cord blood | | | | | | (i) tHcy level [μmol/l] | 12.6 | 7.7 | 8.1 | 0.01 | | (ii) Folate level ng/ml | 13.7 | 14.3 | 15.0 | 0.2 | | (iii) Cobalamin level pg/ml | 300.5 | 425.1 | 325.4 | <0.01 |
| | Mothers | | | | | | (i) tHcy level μmol/l | 7.2 | 7.1 | 6.8 | 0.3 | | (ii) Folate level ng/ml | 10.8 | 14.1 | 15.5 | <0.01 | | (iii) Cobalamin level pg/ml | 198.8 | 269.8 | 258.7 | <0.01 |
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Results are presented as mean and standard deviation SD; value from Kruskal-Wallis test.
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