The Efficacy and Safety of Fractional CO₂ Laser Combined with Topical Type A Botulinum Toxin for Facial Rejuvenation: A Randomized Controlled Split-Face Study

Figure 2

Skin measurements by biophysical evaluation methods were taken at baseline, 1 week, 4 weeks, and 12 weeks after treatment on both sides. (a) Objective measurement of erythema index, (b) melanin index, (c) overall elasticity (R2), (d) hydration, (e) glossy, and (f) TEWL. compared with control side at same time point; compared with baseline.

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