Improvement of Amniotic Membrane Method for the Treatment of Corneal Perforation

Figure 2

Representative images of a perforation caused by a bacterial corneal ulcer before and after AMR treatment. The black bars in the images on the left indicate the areas shown in the OCT images. (a) A perforation on the cornea before intervention. (b) One week after amniotic membrane transplantation (AMT), the overlay AM still covered the entire cornea. (c) Three weeks after AMT, the overlay AM covering was removed, the bilayer AM was partly dissolved, and the anterior chamber depth was close to normal. (d) OCT image 3 weeks after AMT. The loose layer between the AM and the corneal stroma indicated that the AM was not substituted by corneal collagen tissues yet. (e) Image of the eye 1 month after AMT. (f) OCT scan 1 month after AMT. Most of the loose layer between the AM and the corneal stroma had disappeared with a decrease in the stromal thickness. ((g) and (h)) At 36 days after AMT, the OCT scan indicated tight fusion of the AM and corneal stroma. The stromal thickness at the perforation site was slightly thinner than the surrounding stroma, with hyperreflectivity corresponding to corneal scarring.

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