Research Article

Issues around the Prescription of Half Tablets in Northern Switzerland: The Irrational Case of Quetiapine

Table 3

Ten most frequently split medications given by active substances (SPC: Summary of Product Characteristics).

Active substance
(original brand name)
Proportion of split tablets [%] Splitting is explicitly mentioned in the SPC
(yes/no)
Total (cumulative)Quarter
1/4
Half
1/2
Three-quarter 3/4

Pipamperone (Dipiperon)15.86.29.30.3y
Levodopa/decarboxylase inhibitor (Madopar)10.2 (26.0)10.10.1y
Quetiapine (Seroquel, Sequase)6.5 (32.5)0.36.2n
Lorazepam (Temesta)5.1 (37.6)0.44.7y
Mirtazapine (Remeron, generics)4.3 (41.9)4.3y
Torasemide (Torem, generics)3.9 (45.8)2.21.20.5y
Zolpidem (Stilnox, generics)3.2 (49.0)3.2y
Metoprolol (Beloc ZOK, generics)2.7 (51.7)2.7y
Citalopram (Seropram, generics)2.7 (54.4)2.7y
Risperidone (Risperdal)2.6 (57.0)2.6n