Review Article

Preimplantation Exposure to Bisphenol A and Triclosan May Lead to Implantation Failure in Humans

Table 1

The distribution and amount of BPA and TCS in human tissue.

Chemical Tissue typeConcentration References

BPASerum (adult)~1-2 ng/mL[22, 81]
Serum (fetal)~1-2 ng/mL[22]
Breast milk 0.61 ± 0.20 ng/mL[82]
Colostrum3.41 ± 0.13 ng/mL[83]
Follicular fluid~1-2 ng/mL[22]
Amniotic fluid (full term) ~1-2 ng/mL[22]
Amniotic fluid (15–18-week gestation)8.3 ± 8.7 ng/mL[22]
Urine2.75–3.3 μg/g creatinine (~3.00 ng/mL) [84, 85]
Brain0.91 ng/g[10]
Adipose tissue3.78–5.83 ng/g[10, 86]
Liver 1.48 ng/g[10]

TCSSerum4.1–19 ng/g[50]
Breast milk1.3 ± 2.7 ng/g fresh weight[87]
Urine3.55 μg/g creatinine (3.77 ng/mL)[84]
Adipose tissue0.61 ng/g[10]
Liver3.14 ng/g[10]