Research Article
Missense Mutations in Exons 18–24 of EGFR in Hepatocellular Carcinoma Tissues
Table 2
Clinicopathological features of HCC patients which their tissue were determined by IHC.
| Patients () | (%) |
| Age (years) | | <50 | 19 (47.5) | ≥50 | 21 (52.5) | Range | 35–94 | Mean | 51.6 | Median | 50.5 | Sex | | Male | 35 (87.5) | Female | 5 (12.5) | HBsAg | | Negative | 11 (27.5) | Positive | 29 (72.5) | AFP | | <500 ng/mL | 24 (60) | ≥500 ng/mL | 14 (35) | Unknown | 2 (5) | Tumor size | | <5 cm | 13 (32.5) | ≥5 cm | 27 (67.5) | TP53 expression | | Negative | 20 (50) | Positive | 20 (50) | Ki-67 expression | | Negative (10%) | 9 (22.5) | Positive (≥10%) | 31 (77.5) |
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HBsAg: hepatitis B surface antigen; AFP: alpha-fetoprotein; HCC: hepatocellular carcinoma; TP53: tumor protein p53.
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