Research Article

Missense Mutations in Exons 18–24 of EGFR in Hepatocellular Carcinoma Tissues

Table 2

Clinicopathological features of HCC patients which their tissue were determined by IHC.

Patients () (%)

Age (years)
 <5019 (47.5)
 ≥5021 (52.5)
 Range35–94
 Mean51.6
 Median50.5
Sex
 Male35 (87.5)
 Female5 (12.5)
HBsAg
 Negative11 (27.5)
 Positive29 (72.5)
AFP
 <500 ng/mL24 (60)
 ≥500 ng/mL14 (35)
 Unknown2 (5)
Tumor size
 <5 cm13 (32.5)
 ≥5 cm27 (67.5)
TP53 expression
 Negative20 (50)
 Positive20 (50)
Ki-67 expression
 Negative (10%)9 (22.5)
 Positive (≥10%)31 (77.5)

HBsAg: hepatitis B surface antigen; AFP: alpha-fetoprotein; HCC: hepatocellular carcinoma; TP53: tumor protein p53.