Clinical Study

Prospective Evaluation of Whole Genome MicroRNA Expression Profiling in Childhood Acute Lymphoblastic Leukemia

Table 3

Significant miRNAs after validation by real time RT-PCR at day 0 were given. Those miRNAs were reevaluated after 6 months of treatment and the expression change of all miRNAs except miR-128 was significant.

    miRNARR

Validated by RT-PCR (at diagnosis)hsa-miR-128 11.396200
hsa-miR-146a24.372519
hsa-miR-15531.669875
hsa-miR-181a80.630694
hsa-miR-1951.250504

Real time RT-PCR (after 6 months)hsa-miR-1286.073660
hsa-miR-146a0.334798
hsa-miR-1551.201844
hsa-miR-181a4.987600
hsa-miR-1950.206393

RR: relative ratio.