Hepatosplenic Sarcoidosis: Contrast-Enhanced Ultrasound Findings and Implications for Clinical Practice
Figure 5
A 45-year-old woman with history of colon cancer, polycystic ovary syndrome, and migraine, who presented with fatigue, weight loss, and headache. No changes in bowel habits were reported. Physical examination revealed only laterocervical lymphadenopathy. (a) B-mode US documented splenomegaly, with parenchyma subverted by multiple and rounded hypoechoic lesions (arrows). The nodules had maximum size of 22 mm and showed no flow on Color Doppler US. Contrast-enhanced US documented (b) rim-like enhancement of the lesions in the arterial phase (7 seconds, arrows) and hypoenhancement in the parenchymal (c) (1 min 20 sec, arrows) and late phases. In view of the patient history, this pattern was first suggestive of malignancy. However, other organs were normal on second imaging, and histopathological examination revealed noncaseating granulomas, suggesting the diagnosis of splenic sarcoidosis (reprinted with permission from [10]).
