Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome

Table 1

Clinical and laboratory findings for the study’s WM patients.

	Mean value (median value)	Range
Age (years)	65,5 (64)	42–84
Gender (male/female)
IPSS stage	19/17
1	45%
2	39%
3	16%
Bone marrow involvement	46,7% (40%)	5–100%
Lymphadenopathy	21%
Splenomegaly	19%
Hepatomegaly	9%
Extranodal sites	3%
IgM (mg/dL)	2777,2 (2500)	138–7870
Hb (g/dL)	10,9 (11,1)	6–14,3
Platelets (×10^9/L)	233,2 (234)	60–472
WBC (×10^9/L)	7,1 (6,7)	2,1–16,8
B2M (mg/dL)	4,1 (3,4)	1,9–10,4
Abnormal (high) LDH	27%