Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with <i>MYD88</i> L265P Somatic Mutation Status, Clinical Features, and Outcome

<table>Electropherogram—after capillary electrophoresis in Agilent 2100 Bioanalyzer using Agilent DNA 1000 kit (Agilent Technologies)—of<i> IGHV6</i>-PCR product in one of the two patients of whom genomic DNA was extracted from blood sample and not bone marrow. Monoclonality of<i> IGHV</i>-PCR product is obvious (peak number 2) and was further confirmed by direct sequencing.</table>

BioMed Research International

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Figure 1

Figure 1: Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with <i>MYD88</i> L265P Somatic Mutation Status, Clinical Features, and Outcome 

Figure 1 | Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome 