Intensive Insulin Therapy for Septic Patients: A Meta-Analysis of Randomized Controlled Trials

Table 3

Sensitivity analysis.

Outcome	Number of; studies	Number of; patients	RR (95% CI)	𝑃 value
Low risk of random sequence generation and allocation concealment
Mortality	6	3478	1.04 (0.95–1.15)	0.40
Hypoglycemia	4	2059	3.27 (1.62–6.57)	0.0009
Trials containing >500 patients
Mortality	4	3293	1.04 (0.94–1.14)	0.44
Hypoglycemia	3	1996	3.81 (1.89–7.69)	0.0002
Patients with similar baseline
Mortality	9	1910	1.00 (0.89–1.13)	0.97
Hypoglycemia	7	2213	2.93 (1.69–5.06)	0.0001
Patients with septic shock
Mortality	4	1533	1.03 (0.89–1.18)	0.69
Hypoglycemia	4	1535	2.97 (1.72–5.12)	<0.0001

RR: risk ratio; CI: confidence interval.