Research Article
Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma
Table 3
Predictive value of conventional US features and ARFI in 173 thyroid lesions.
| | | BN
() | CA
() | Sensitivity
(%) | Specificity
(%) | PPV
(%) | NPV
(%) | Accuracy
(%) | Az
(95% CI) |
| | US features | | | | | | | | | Hypoechoic
(including markedly hypoechoic) | | | 94.8
(91/96) | 27.3
(21/77) | 61.9
(91/147) | 80.8
(21/26) | 64.7
(112/173) | 0.610*
(0.524, 0.696) | | Yes | 56 | 91 | | | | | | | | No | 21 | 5 | | | | | | | | Spot microcalcification | | | 55.2
(53/96) | 71.4
(55/77) | 70.7
(53/75) | 56.1
(55/98) | 62.4
(108/173) | 0.633*
(0.550, 0.716) | | Yes | 22 | 53 | | | | | | | | No | 55 | 43 | | | | | | | | Shape (taller than wide) | | | 54.2
(52/96) | 83.1
(64/77) | 80
(52/65) | 59.3
(64/108) | 67.1
(116/173) | 0.686
(0.607, 0.766) | | Yes | 13 | 52 | | | | | | | | No | 64 | 44 | | | | | | | | Halo sign | | | 99.0
(95/96) | 9.1
(7/77) | 57.6
(95/165) | 87.5
(7/8) | 59.0
(102/173) | 0.540*
(0.453, 0.627) | | Yes | 7 | 1 | | | | | | | | No | 70 | 95 | | | | | | | | Type III vascularity | | | 17.7
(17/96) | 88.3
(68/77) | 65.4
(17/26) | 46.2
(68/147) | 49.1
(85/173) | 0.455*
(0.368, 0.542) | | Yes | 9 | 17 | | | | | | | | No | 68 | 79 | | | | | | | | ARFI features | | | | | | | | | VTI
Elastography score > 4 | | | 61.4
(59/96) | 88.3
(68/77) | 86.8
(59/68) | 64.8
(68/105) | 73.4
(127173) | 0.746
(0.672, 0.850) | | Yes | 9 | 59 | | | | | | | | No | 68 | 37 | | | | | | | VTQ
SWV > 3.10 m/s | | | 56.2
(54/96) | 79.2
(61/77) | 77.1
(54/70) | 59.2
(61/103) | 66.5
(115/173) | 0.702
(0.625, 0.780) | | Yes | 16 | 54 | | | | | | | | No | 61 | 42 | | | | | | |
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Caption: BN, benign; CA, carcinoma; US, ultrasound; PPV, positive predictive value; NPV, negative predictive value.
In comparison with “VTI elastography score > 4”, .
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