TY - JOUR A2 - Barr, Richard G. AU - Zhang, Yi-Feng AU - Liu, Chang AU - Xu, Hui-Xiong AU - Xu, Jun-Mei AU - Zhang, Jing AU - Guo, Le-Hang AU - Zheng, Shu-Guang AU - Liu, Lin-Na AU - Xu, Xiao-Hong PY - 2014 DA - 2014/06/22 TI - Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma SP - 416969 VL - 2014 AB - Purpose. To evaluate the diagnostic performance of ARFI imaging in differentiating between benign and malignant thyroid nodules <1 cm. Materials and Methods. 173 pathologically proven thyroid nodules (77 benign, 96 malignant) in 157 patients were included in this study. Receiver-operating characteristic curve (ROC) analyses were performed to assess the diagnostic performance of conventional ultrasound (US) and ARFI imaging in papillary thyroid microcarcinoma (PTMC). The independent risk factors for predicting PTMC were evaluated. Results. The mean SWV value of benign and malignant thyroid nodules were 2.57 ± 0.79 m/s (range: 0.90–4.92 m/s) and 3.88 ± 2.24 m/s (range: 1.49–9.00 m/s) (P=0.000). Az for VTI elastography score was higher than that for hypoechoic, absence of halo sign, and type III vascularity (P<0.05). The optimal cut-offs for VTI elastography score and SWV were score 4 and 3.10 m/s. Gender, hypoechoic, taller than wide, VTI elastography score ≥ 4, and SWV > 3.10 m/s had been found to be independent risk factors for predicting PTMC. Conclusion. ARFI elastography can provide elasticity information of PTMC quantitatively (VTQ) and directly reflects the overall elastic properties (VTI). Gender, hypoechogenicity, taller than wide, VTI elastography score ≥ 4, and SWV > 3.10 m/s are independent risk factors for predicting PTMC. ARFI elastography seems to be a new tool for the diagnosis of PTMC. SN - 2314-6133 UR - https://doi.org/10.1155/2014/416969 DO - 10.1155/2014/416969 JF - BioMed Research International PB - Hindawi Publishing Corporation KW - ER -