The Modulatory Effect of Ellagic Acid and Rosmarinic Acid on Ultraviolet-B-Induced Cytokine/Chemokine Gene Expression in Skin Keratinocyte (HaCaT) Cells

Figure 3

Assessment of cytokine gene expression in HaCaT cells incubated with EA (5 μM in 0.1% DMSO) or RA (2.75 μM in 0.5% DMSO) immediately after UVB exposure (100 mJ/cm²), through qRT-PCR. ((a), (b), and (c)) IL-1β, IL-6, and IL-8 gene expression in cells incubated immediately after UVB irradiation with EA or RA for 6 h; ((d), (e), and (f)) IL-10, MCP-1, and TNF-α gene expression in cells incubated immediately after UVB irradiation with EA or RA for 24 h. (^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001; ns: not statistically significant).

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