Research Article

Deposition of Doxorubicin in Rats following Administration of Three Newly Synthesized Doxorubicin Conjugates

Figure 1

DOX plasma concentration after intravenous administration. (a) Free DOX and (b) total DOX were released from DOX-LNA, PEG-ami-DOX, and PEG-hyd-DOX following a single intravenous administration of 5 mg/kg (DOX equivalent) to SD rats. Each point and bar represents the mean ± SD ( ).
926584.fig.001a
(a)
926584.fig.001b
(b)