Review Article

Highlights from the Functional Single Nucleotide Polymorphisms Associated with Human Muscle Size and Strength or FAMuSS Study

Table 1

FAMuSS findings: genetic loci associated with muscle size and strength at baseline and in response to resistance training.

GeneNameReference

ACE Angiotensin I converting enzyme[19]
ACTN3Actinin, alpha 3[14]
ANKRD6Ankyrin repeat domain 6[24]
BMP2Bone morphogenetic protein 2[15]
CCL2Chemokine (C-C motif) ligand 2[17]
CCR2Chemokine (C-C motif) receptor 2[17]
CNTF Ciliary neurotrophic factor[26]
FST Follistatin[20]
GDF8 /MSTN Growth differentiation factor 8/myostatin[20]
IGF1Insulin-like growth factor 1[21]
IL15Interleukin 15[23]
IL 15RαInterleukin 15 receptor, alpha[23]
LEP Leptin[25]
LEPR Leptin receptor[25]
NOS3Nitric oxide synthase 3[16]
RETN Resistin[22]
SPP1Osteopontin or secreted phosphoprotein 1[18]