The Protective Effect of Fasudil on the Structure and Function of Cardiac Mitochondria from Rats with Type 2 Diabetes Induced by Streptozotocin with a High-Fat Diet Is Mediated by the Attenuation of Oxidative Stress

Table 2

Comparison of oxidative stress biomarkers in diabetic rats either treated with or without fasudil.

	Fasudil-treated diabetic group (𝑛=10)	Untreated diabetic group (𝑛=10)	Control group; (𝑛=10)
TAC (mmol/mg protein)	13.03 ± 2.46^#	9.77 ± 1.14*	13.76 ± 3.60
MDA (mmol/mg protein)	3.02 ± 0.49^#	4.65 ± 0.57*	2.88 ± 1.21
hydroxy radical (nmol/mg protein)	0.59 ± 0.15^#	0.94 ± 0.15*	0.53 ± 0.14
GSH (μmol/mg protein)	14.16 ± 2.47^#	9.13 ± 2.06*	14.61 ± 5.07
SOD (U/mg protein)	0.66 ± 0.28^#*	0.38 ± 0.20*	1.27 ± 0.83

Data are presented as the mean ± SD.
* 𝑃<0.05 versus control group.
^#𝑃<0.05 versus untreated diabetic group.