Review Article

The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes

Figure 2

Inhibition of A2B receptor in CD73KO mice increases susceptibility to MLDS-induced diabetes. Diabetes incidence of CD73KO mice treated with either saline (open triangles, 𝑛 = 6 ) or the A2BR inhibitor (dose: 0.5 μg/g body weight (BW), twice daily) (black triangles, 𝑛 = 6 ). * 𝑃 < 0 . 0 5 versus saline-treated mice.
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