Molecular Imaging, Pharmacokinetics, and Dosimetry of ¹¹¹In-AMBA in Human Prostate Tumor-Bearing Mice

Table 3

Radiation dose estimates for ¹¹¹In-AMBA in humans.

Organ	Estimated dose (mSv/MBq^−1)*
Adrenals	1.5𝐸−01
Brain	3.1𝐸−02
Breasts	7.7𝐸−02
Gallbladder Wall	1.5𝐸−01
LLI Wall	1.2𝐸−01
Small Intestine	1.3𝐸−01
Stomach Wall	1.1𝐸−01
ULI Wall	1.3𝐸−01
Heart Wall	7.2𝐸−02
Kidneys	1.2𝐸−01
Liver	2.0𝐸−01
Lungs	7.4𝐸−02
Muscle	7.0𝐸−02
Ovaries	1.2𝐸−01
Pancreas	2.5𝐸−01
Red Marrow	8.8𝐸−02
Osteogenic Cells	2.2𝐸−01
Skin	5.8𝐸−02
Spleen	1.2𝐸−01
Testes	5.9𝐸−02
Thymus	9.0𝐸−02
Thyroid	9.2𝐸−02
Urinary Bladder Wall	1.1𝐸−01
Uterus	1.3𝐸−01
Total Body	9.2𝐸−02
Effective Dose	1.1𝐸−01

*Radiation-absorbed dose projections in humans were determined from residence times for ¹¹¹In-AMBA in SCID mice and were calculated by use of OLINDA/EXM version 1.0 computer program.