Biomarkers that correlate with prognosis in lupus nephritis.
|Authors, year||Biomarkers studied||Main findings|
|Izmirly et al., 2009 ||mEPCR expression on renal biopsy||Membrane expression of endothelial protein C receptor (mEPCR) in the renal microvasculature in lupus nephritis associated with poor therapeutic response|
|Avihingsanon et al., 2009 ||VEGF expression||Intrarenal vascular endothelial growth factor (VEGF) mRNA expression predicted the deterioration of renal function in lupus nephritis|
|Marks et al., 2008 ||Glomerular MCP-1 expression||Glomerular monocyte chemoattractant protein-1 (MCP-1) expression associated with poor renal prognosis in pediatric lupus nephritis|
|Oates et al., 2008 ||Serum nitrate and nitrite levels||Higher serum nitrate plus nitrite levels associated with renal damage and treatment failure in lupus nephritis|
|Martinez-Lostao et al., 2007 ||STAT-1 expression on renal biopsy||Expression of STAT-1 in renal tissues associated with worse renal function and outcome in class IV lupus nephritis|
|Avihingsanon et al., 2006 ||Chemokine and growth factor mRNA levels in urinary sediments||Persistent elevation or increase of urine interferon-producing protein 10 (IP-10), CXCR3, TGF-, and VEGF mRNA levels associated with treatment failure in lupus nephritis|