Genome-Wide Transcriptional Profiling of the Response of Staphylococcus aureus to Cryptotanshinone

Table 3

Real-time RT-PCR analysis of gene expression.

N315 ORF	N315 gene	N315 description	Fold change ± SD^(a)
			RT-PCR	Microarray
SA1587	ribA	Riboflavin biosynthesis protein	−3.8±1.9	−2.5±1.3
SA0977	isdA	Cell surface protein	−4.3±2.3	−3.2±1.0
SA2074	modA	Probable molybdate-binding protein	−2.8±0.9	−2.5±0.8
SA1648	seo	Enterotoxin SeO [Pathogenicity island SaPIn3]	−3.8±1.2	−2.5±0.6
SA1831		Hypothetical protein [Pathogenicity island SaPIn1]	−19.4±6.1	−6.1±1.6
SA0982	srtB	NPQTN specific sortase B	−3.2±0.8	−3.0±1.1
SA0325	glpT	Glycerol-3-phosphate transporter	−2.7±0.3	−2.8±0.4
SA0198	oppF	Oligopeptide transport ATP-binding protein	−2.8±0.5	−2.5±0.8
SA2135		Hypothetical protein, similar to sodium/glutamate symporter	−2.8±0.8	−2.1±0.8
SA0206	msmX	Multiple sugar-binding transport ATP-binding protein	−3.4±1.0	−2.5±0.8
SA2251	opp-1F	Oligopeptide transporter putative ATPase domain	−2.6±0.7	−2.6±0.6
SA1941	dps	General stress protein 20U	10.5±2.8	4.9±1.6
SA0302		Probable pyrimidine nucleoside transport protein	18.4±5.4	6.1±1.7

^(a)+ indicates reduction, and − indicates increase. Standard deviation were calculated based on three independent experiments.