Bone Marrow Research / 2013 / Article / Tab 1 / Clinical Study
Day 100 Peripheral Blood Absolute Lymphocyte/Monocyte Ratio and Survival in Classical Hodgkin's Lymphoma Postautologous Peripheral Blood Hematopoietic Stem Cell Transplantation Table 1 Baseline patient characteristics.
Characteristics
(%)Median Range At diagnosis Age, years 131 (100%) 32 (18–68) Gender Male 67 (51%) Female 64 (49%) Albumin (g/dL) 127 (97%) 4 (2.0–4.6) ALC × 109 /L 131 (100%) 1.3 (0.2–2.9) Hemoglobin (g/dL) 131 (100%) 12.2 (7.7–16.2) Mediastinal disease ≥10 cm 21 (16%) <10 cm 110 (84%) Stage I 6 (4%) II 56 (43%) III 35 (27%) IV 34 (26%) Stage Limited 61 (47%) Advanced 69 (53%) WBC × 109 /L 131 (100%) 8.3 (1.4–22.2) IPS risk factors Age, years ≤45 109 (83%) >45 22 (17%) Albumin (g/dL) (
= 127) ≥4 80 (63%) <4 47 (37%) ALC × 109 /L ≥0.6 106 (81%) <0.6 25 (19%) Hemoglobin (g/dL) >10.5 102 (78%) ≤10.5 29 (22%) Male 67 (51%) Stage 4 34 (26%) WBC × 109 /L >15 20 (15%) ≤15 111 (85%) IPS score 0 30 (23%) 1 41 (31%) 2 27 (21%) 3 13 (10%) 4 10 (8%) 5 7 (5%) 6 3 (2%) IPS index ≥3 33 (25%) <3 98 (75%) At transplant Infused CD34+ stem cell × 106 /kg 131 (100%) 5.1 (2.1–15.8) Pretransplant response CR 30 (23%) PR 101 (77%) At Day 15 post-APBHSCT ALC × 109 /L 131 (100%) 0.67 (0.1–3.67) ALC × 109 /L ≥0.5 90 (69%) <0.5 41 (31%) At day 100 post-APBHSCT Age, years 131 (100%) 35 (18–69) Hemoglobin (g/dL) 131 (100%) 11.9 (7.3–16.7) WBC × 109 /L 131 (100%) 4.4 (1.5–14.3) ANC × 109 /L 131 (100%) 2.54 (1.2–10.01) ALC × 109 /L 131 (100%) 1.09 (0.15–4.61) AMC × 109 /L 131 (100%) 0.46 (0.15–4.02) ALC/AMC 131 (100%) 2.5 (0.18–11.07) Plts × 109 /L 131 (100%) 164 (55.2–373)
Abbreviations: ALC: absolute lymphocyte count; ANC: absolute neutrophil count; AMC: absolute monocyte count; CR: complete remission; IPS: International Prognostic Score; PR: partial response; Plts: platelets; and WBC: white blood cell count.