TY - JOUR A2 - Atieh, Muataz A. AU - Shah, Syed Niaz Ali AU - Shah, Zahir AU - Hussain, Muzammal AU - Khan, Muzaffar PY - 2017 DA - 2017/03/08 TI - Hazardous Effects of Titanium Dioxide Nanoparticles in Ecosystem SP - 4101735 VL - 2017 AB - Although nanoparticles (NPs) have made incredible progress in the field of nanotechnology and biomedical research and their applications are demanded throughout industrial world particularly over the past decades, little is known about the fate of nanoparticles in ecosystem. Concerning the biosafety of nanotechnology, nanotoxicity is going to be the second most priority of nanotechnology that needs to be properly addressed. This review covers the chemical as well as the biological concerns about nanoparticles particularly titanium dioxide (TiO2) NPs and emphasizes the toxicological profile of TiO2 at the molecular level in both in vitro and in vivo systems. In addition, the challenges and future prospects of nanotoxicology are discussed that may provide better understanding and new insights into ongoing and future research in this field. SN - 1565-3633 UR - https://doi.org/10.1155/2017/4101735 DO - 10.1155/2017/4101735 JF - Bioinorganic Chemistry and Applications PB - Hindawi KW - ER -