Advances in Virology

Virus Variability and Its Impact on HIV and Hepatitis Therapy


Publishing date
08 Jun 2012
Status
Published
Submission deadline
09 Dec 2011

1HIV, Hepatitis & Global Health Unit, Istituto Superiore di Sanità, Rome, Italy

2Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanità, Rome, Italy

3Department of Internal Medicine I, University of Bonn, Bonn, Germany

4Department of Public Medicine, Section of Infectious Diseases, Second University of Naples, Naples, Italy


Virus Variability and Its Impact on HIV and Hepatitis Therapy

Description

HIV, HCV, and HBV are genetically heterogeneous, including a broad spectrum of genotypes and subtypes. Both genotypes and their subtypes show a varied prevalence globally and raise several issues related to their transmission and treatment. The emergence of resistance-associated mutations to the antiviral agents and the genetic variability impose challenges to therapeutic success. All this information has a great significance while planning future strategies for eradication and therapeutic management. For example, regional surveillance of the resistance profile and subtypes circulation is crucial in the context of public health, to prevent the transmission of resistant strains and to guide the introduction of new drugs in a specific population.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular epidemiology of HIV and hepatitis viruses, its relationship with therapeutic strategies, the insurgence of resistant mutations first of all to the new antiviral compounds, and the association with human genome variability. Potential topics include, but not limited to:

  • Genetic signatures in HIV and hepatitis genes correlated with different outcomes of therapy
  • HIV and hepatitis genetic evolution in longitudinally followed patients
  • Spread of subtypes and recombinants
  • Identification of biomarkers of treatment response
  • Role of host-related genetic markers in the response to antiviral therapy
  • Correlation between host immune response and viruses variability

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/av/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 607527
  • - Editorial

Virus Variability and Its Impact on HIV and Hepatitis Therapy

Domenico Genovese | Christoph Boesecke | ... | Stefano Vella
  • Special Issue
  • - Volume 2012
  • - Article ID 123605
  • - Review Article

Impact of Tat Genetic Variation on HIV-1 Disease

Luna Li | Satinder Dahiya | ... | Brian Wigdahl
  • Special Issue
  • - Volume 2012
  • - Article ID 267483
  • - Review Article

Hepatitis C Variability, Patterns of Resistance, and Impact on Therapy

Cristina Simona Strahotin | Michael Babich
  • Special Issue
  • - Volume 2012
  • - Article ID 548657
  • - Research Article

In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors

Xiaoju Ni | Safwat Abdel-Azeim | ... | Luba Tchertanov
  • Special Issue
  • - Volume 2012
  • - Article ID 434036
  • - Review Article

Glances in Immunology of HIV and HCV Infection

Maria Giovanna Quaranta | Benedetta Mattioli | Stefano Vella
  • Special Issue
  • - Volume 2012
  • - Article ID 508967
  • - Review Article

Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response

Raghavan Sampathkumar | Elnaz Shadabi | Ma Luo
  • Special Issue
  • - Volume 2012
  • - Article ID 637208
  • - Review Article

Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development

Gamze Isitman | Ivan Stratov | Stephen J. Kent
  • Special Issue
  • - Volume 2012
  • - Article ID 803535
  • - Research Article

Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies

David Almond | Chavdar Krachmarov | ... | Timothy Cardozo
Advances in Virology
 Journal metrics
Acceptance rate7%
Submission to final decision52 days
Acceptance to publication49 days
CiteScore1.970
Impact Factor-
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