Research Article

Hepatitis B Virus Immunity Gap: A Six-Year Laboratory Data Review of Hepatitis B Serological Profiles in Gauteng Province, South Africa

Table 6

Summary of patients by age groups who were HBV-infected, had natural and vaccine-induced immunity, or were at risk of HBV infection in Gauteng Province, South Africa, from 2014 to 2019 ().

InterpretationAge groups n (%)Total
<5 years5–12 years13–24 years≥25 years

HBV-infected: HBsAg pos; anti-HBc total pos; anti-HBs neg21 (2.0)42 (3.1)272 (4.2)3,431 (8.0)3,766 (7.0)
HBV naturally acquired immunity: HBsAg neg; anti-HBc total pos; anti-HBs pos113 (10.0)45 (3.4)541 (8.3)11,188 (26.0)11,887 (23.0)
HBV vaccine immunity: HBsAg neg; anti-HBc total neg; anti-HBs pos656 (57.0)686 (51.5)1,757 (27.0)4,425 (10.0)7,524 (14.0)
HBV seronegative group: HBsAg neg; anti-HBc total neg; anti-HBs neg368 (31.0)560 (42.0)3,952 (60.5)24,524 (56.0)29,404 (56.0)
Total1,158 (2.0)1,333 (2.5)6,522 (12.4)43,536 (83.0)52,581 (100.0)