Detection of HIV-1 and Human Proteins in Urinary Extracellular Vesicles from HIV+ Patients

Table 8

Functional enrichment analysis of control EV proteins.

	Genes in the database	Genes in the Bkg. database	Percentage of genes	Fold enrichment	Corrected value (BH FDR )
Site of expression
Cervicovaginal fluid	16	544	12.0	4.2
Neutrophils	13	392	9.7	4.8
Gastric juice	9	222	6.7	6.1
Molecular function
Defense/immunity protein activity	5	52	3.7	15.7
Biological process
Immune response	13	561	9.8	3.4	0.00026
Signal transduction	43	3907	32.5	1.5	0.0026
Cell communication	41	3687	31.1	1.5	0.0028
Antigen presentation	1	1	0.7	134.4	0.0073