Research Article

A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus

Table 2

Top hundred differentially expressed genes identified in dataset GSE6802.

ProbeIDGene symbolGene name fold changeFDR

212615_atCHD9Chromodomain helicase DNA binding protein 9−3,696090,00131
221840_atPTPREProtein tyrosine phosphatase, receptor type E−3,565240,000195
220817_atTRPC4Transient receptor potential cation channel subfamily C member 4−3,391680,001582
221703_atBRIP1BRCA1 interacting protein C-terminal helicase 1−2,887860,021463
207012_atMMP16Matrix metallopeptidase 16−2,826470,000119
219494_atRAD54BRAD54 homolog B (S. cerevisiae)−2,812790,000177
207034_s_atGLI2GLI family zinc finger 2−2,797230,005157
203518_atLYSTLysosomal trafficking regulator−2,758725,90E − 05
205282_atLRP8LDL receptor related protein 8−2,75490,000311
214440_atNAT1N-Acetyltransferase 1 (arylamine N-acetyltransferase)−2,685150,001777
219627_atZNF767PZinc finger family member 767, pseudogene−2,679570,00024
218984_atPUS7Pseudouridylate synthase 7 (putative)−2,675860,001308
206554_x_atSETMARSET domain and mariner transposase fusion gene−2,635360,002432
219779_atZFHX4Zinc finger homeobox 4−2,626240,001411
213103_atSTARD13StAR related lipid transfer domain containing 13−2,572190,002525
210138_atRGS20Regulator of G-protein signaling 20−2,559740,000415
204291_atZNF518AZinc finger protein 518A−2,543839,70E − 05
204651_atNRF1Nuclear respiratory factor 1−2,491470,003659
205408_atMLLT10Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10−2,489755,10E − 05
219581_atTSEN2tRNA splicing endonuclease subunit 2−2,453770,001774
218242_s_atSUV420H1Lysine methyltransferase 5B−2,446980,000754
203242_s_atPDLIM5PDZ and LIM domain 5−2,438510,001699
203868_s_atVCAM1Vascular cell adhesion molecule 1−2,435130,000761
220206_atZMYM1Zinc finger MYM-type containing 1−2,363620,008439
207616_s_atTANKTRAF family member associated NFKB activator−2,345670,000424
218303_x_atKRCC1Lysine-rich coiled-coil 1−2,345670,003187
218490_s_atZNF302Zinc finger protein 302−2,327850,001816
206876_atSIM1Single-minded family bHLH transcription factor 1−2,326240,001681
219128_atC2orf42Chromosome 2 open reading frame 42−2,286280,002926
212861_atMFSD5Major facilitator superfamily domain containing 5−2,270480,000823
218653_atSLC25A15Solute carrier family 25 member 15−2,256360,000562
206943_atTGFBR1Transforming growth factor beta receptor I−2,248560,025349
201995_atEXT1Exostosin glycosyltransferase 1−2,2470,000421
221430_s_atRNF146Ring finger protein 146−2,234570,001084
212286_atANKRD12Ankyrin repeat domain 12−2,22530,00029
219544_atBORABora, aurora kinase A activator−2,219140,000333
210455_atR3HCC1LR3H domain and coiled-coil containing 1 like−2,21760,0039
219459_atPOLR3BPolymerase (RNA) III subunit B−2,21760,000832
219078_atGPATCH2G-patch domain containing 2−2,199230,000723
204547_atRAB40BRAB40B, member RAS oncogene family−2,176480,001741
209760_atKIAA0922KIAA0922−2,173470,001048
218791_s_atKATNBL1Katanin regulatory subunit B1 like 1−2,173470,001187
205173_x_atCD58CD58 molecule−2,171960,00022
204352_atTRAF5TNF receptor associated factor 5−2,168950,002659
212441_atKIAA0232KIAA0232−2,165950,006084
204236_atFLI1Fli-1 proto-oncogene, ETS transcription factor−2,153970,005141
203072_atMYO1EMyosin IE−2,152480,000154
219904_atZSCAN5AZinc finger and SCAN domain containing 5A−2,148010,00144
219133_atOXSM3-Oxoacyl-ACP synthase, mitochondrial−2,122850,002424
205798_atIL7RInterleukin 7 receptor−2,112570,00506
205476_atCCL20C-C motif chemokine ligand 204,6139429,50E − 05
213497_atABTB2Ankyrin repeat and BTB domain containing 24,6235471,40E − 05
219179_atDACT1Dishevelled-binding antagonist of beta-catenin 14,6428169,00E − 06
219228_atZNF331Zinc finger protein 3314,7239716,00E − 06
213139_atSNAI2Snail family zinc finger 24,766731,40E − 05
218177_atCHMP1BCharged multivesicular body protein 1B4,8065441,00E − 05
203304_atBAMBIBMP and activin membrane-bound inhibitor4,8265763,00E − 06
201631_s_atIER3Immediate early response 34,8332713,00E − 06
218559_s_atMAFBv-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B4,8702640,000468
220266_s_atKLF4Kruppel-like factor 4 (gut)4,8905610,00022
209211_atKLF5Kruppel-like factor 5 (intestinal)4,9245780,002036
209681_atSLC19A2Solute carrier family 19 member 24,9279925,90E − 05
205266_atLIFLeukemia inhibitory factor4,9553952,20E − 05
204790_atSMAD7SMAD family member 75,0735660,000283
221667_s_atHSPB8Heat shock protein family B (small) member 85,4226572,90E − 05
212665_atTIPARPTCDD-inducible poly(ADP-ribose) polymerase5,5250981,00E − 05
202935_s_atSOX9SRY-box 95,9711143,30E − 05
202023_atEFNA1Ephrin-A16,1645693,30E − 05
202393_s_atKLF10Kruppel-like factor 106,1945520,000195
213146_atKDM6BLysine demethylase 6B6,2031461,90E − 05
205193_atMAFFv-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F6,29412,00E − 06
209457_atDUSP5Dual specificity phosphatase 56,6391571,30E − 05
206029_atANKRD1Ankyrin repeat domain 16,657590,008591
209283_atCRYABCrystallin alpha B6,7038970,000118
201693_s_atEGR1Early growth response 17,0567314,10E − 05
212099_atRHOBras homolog family member B7,3005240,000406
219682_s_atTBX3T-box 37,7221365,80E − 05
201473_atJUNBjun B proto-oncogene8,3224027,00E − 06
200664_s_atDNAJB1DnaJ heat shock protein family (Hsp40) member B18,5860822,00E − 05
205828_atMMP3Matrix metallopeptidase 38,7119761,90E − 05
201169_s_atBHLHE40Basic helix-loop-helix family member e408,8704050,00011
203665_atHMOX1Heme oxygenase 19,324330,000544
202643_s_atTNFAIP3TNF alpha induced protein 39,5731922,50E − 05
205207_atIL6Interleukin 610,182363,00E − 06
202388_atRGS2Regulator of G-protein signaling 210,253181,40E − 05
204472_atGEMGTP binding protein overexpressed in skeletal muscle10,80031,00E − 06
202149_atNEDD9Neural precursor cell expressed, developmentally down-regulated 911,065532,50E − 05
219480_atSNAI1Snail family zinc finger 111,704572,00E − 06
218839_atHEY1hes related family bHLH transcription factor with YRPW motif 112,075416,00E − 06
206115_atEGR3Early growth response 314,191941,20E − 05
204470_atCXCL1C-X-C motif chemokine ligand 117,618272,00E − 06
204621_s_atNR4A2Nuclear receptor subfamily 4 group A member 218,778370
209774_x_atCXCL2C-X-C motif chemokine ligand 219,027319,00E − 06
202859_x_atCXCL8C-X-C motif chemokine ligand 819,890391,00E − 06
202340_x_atNR4A1Nuclear receptor subfamily 4 group A member 120,749431,00E − 06
209189_atFOSFBJ murine osteosarcoma viral oncogene homolog23,360511,00E − 06
202672_s_atATF3Activating transcription factor 324,184320
202768_atFOSBFBJ murine osteosarcoma viral oncogene homolog B32,922450
207978_s_atNR4A3Nuclear receptor subfamily 4 group A member 343,804281,00E − 06
117_atHSPA6Heat shock protein family A (Hsp70) member 690,823890