Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development
Figure 1
HIV-specific immune responses force immune escape. The mechanism of immune pressure applied by Cytotoxic T lymphocytes (a), neutralizing antibodies (b), and ADCC antibodies (1) is illustrated. Escape from immune responses shows results once free virus (Nab responses) or viral particles are presented either via the MHC class pathway (CTL responses) or possibly on the surface of the infected cell by virus budding (ADCC).
