Histoprotective Effect of Essential Oil from Citrus aurantifolia in Testosterone-Induced Benign Prostatic Hyperplasia Rat

Figure 6

Photomicrographs of seminiferous tubules in testis of various experimental groups: (a) sham; (b) model, TE (10 mg/kg)/olive oil injection (i.m.); (c) finasteride, positive control, TE (10 mg/kg)/olive oil injection (i.m. + finasteride administration (15 mg/kg, p.o.); (d) small dose, TE (10 mg/kg) olive oil injection (i.m.) + LEO (30 mg/kg); (e) medium dose, TE (10 mg/kg)/olive oil injection (i.m.) + LEO (100 mg/kg); (f) high dose, TE (10 mg/kg)/olive oil injection (i.m.) + LEO (300 mg/kg). The red arrow represents seminiferous tubules, and blue arrow represents eosinophilic secretion in intertubular space. When compared to the sham group, model group had seminiferous tubules with less compact or eroded germinal epithelium and eosinophilic secretion in the tubulointerstitium. Finasteride-treated group had few seminiferous tubules with vacuolated epithelium. All lime essential oil-treated groups had seminiferous with intact epithelium similar to the sham group.

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