Histoprotective Effect of Essential Oil from Citrus aurantifolia in Testosterone-Induced Benign Prostatic Hyperplasia Rat

Figure 2

Mean serum PSA level before and after treatment for various experimental groups. Data are presented as mean ± standard error of mean (n = 6) (ns = no significance, and ). B represents before treatment, and A represents after treatment. There was a decrease in the serum PSA levels of all treatment groups compared to the disease control (testosterone) group. The low-dose, mid-dose, and high-dose Citrus aurantifolia groups all produced a significant reduction in serum PSA levels, together with the finasteride and normal control groups. This implies that the reduction in serum PSA levels was statistically significant, upon treatment with all doses of Citrus aurantifolia. A greater and more significant decrease was observed in the high-dose group than the low-dose and the mid-dose groups.