Research Article
Efficacy of Transdermal Oxybutynin in the Treatment of Overactive Bladder Syndrome: Does It Make Sense Using It in 2017?
Table 3
Changes 3D from baseline in the 3 DVD tool at 12 months of treatment with OXY-TDS (naive/nonnaive patients).
| 3 DVD | Naive () mean (SD) | Nonnaive () mean (SD) | Diff (95% CI) | value |
| DUF (episodes/day) | 7.07 (1.8) | 6.9 (1.5) | 0.4 (−0.7; 1.3) | 0.341 | NUF (episodes/night) | 0.87 (0.7) | 0.7 (0.8) | 0.0 (−3.0; 0.7) | 0.411 | UF/24 hours (episodes/day) | 8.0 (2.1) | 7.6 (1.7) | 6.3 (−0.4; 1.7) | 0.298 | Maximum UV (ml) | 444.6 (486.1) | 302.1 (83.1) | 24.1 (−41.7; 100.0) | 0.461 | Nocturnal UV (ml) | 112.6 (84.9) | 143.83 (168.9) | −31.2 (−135.9; 73.5) | 0.550 | Mean UV (ml) | 205.5 (54.9) | 191.0 (NA) | 14.5 (−180.6; 209.6) | 0.828 | Urgency (episodes/day) | 1.5 (2.1) | 1.5 (1.2) | 0.5 (−0.9; 1.0) | 0.892 | Urgency grade | 1.8 (1.3) | 2.5 (1.3) | −0.7 (−1.3; 0.0) | 0.071 | UUI (episodes/day) | 0.2 (0.5) | 0.6 (1.0) | 0.0 (−0.3; 0.0) | 0.328 | SUI (episodes/day) | 0.0 (0.0) | 0.2 (0.6) | 0.0 (0.0; 0.0) | 0.110 | Pad/underwear changes (number/day) | 0.6 (1.0) | 0.8 (1.1) | 0.0 (−0.6; 0.0) | 0.044 | Liquid intake/24 h (ml) | 1484.73 (613.5) | 1439.0 (481.9) | 45.7 (−326.4; 417.1) | 0.805 | Urine output/24 h (ml) | 1609.17 (446.6) | 1457.89 (347.2) | 151.3 (−115.5; 418.0) | 0.258 | Nocturnal urine output (ml) | 167.77 (138.3) | 185.26 (228.2) | −17.5 (−162.6; 127.6) | 0.808 |
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3 DVD: 3-day voiding diary; DUF: daytime urinary frequency; NUF: night-time urinary frequency; SD: standard deviation; SUI: stress urinary incontinence; UF/24 h: 24-hour urinary frequency (total number of episodes/24 hours); UUI: urge urinary incontinence. values: Student’s t-test or Wilcoxon signed rank test. Change: mean difference, or Hodges-Lehman estimator of location shift. |