Review Article
A Review of the Effect of Injected Dextranomer/Hyaluronic Acid Copolymer Volume on Reflux Correction Following Endoscopic Injection
Table 2
Studies
investigating the effect of injected Dx/HA volume on VUR correction.
| Series | Refluxing units; mean | Mean | Volume injected (mL) | Method of statistical | Success by | Effect of volume of | Dx/HA volume (mL) | grade | success/failures | analysis | grade
(%) | injected Dx/HA |
| Kirsch 2003 | 292 | 2.6 | S: | Univariate | I 90; II 82; | NS | | F: | III 73; IV 65 |
| Kirsch 2004 | 119
| | S: 1.0 | | I 100; II 90; | Higher | modified | | 2.8 | F: 1.5 | Univariate | III 91; IV
89 | volume | STING | | | | | | significant |
| Lavelle | 80 | NA | S: 0.8 | Univariate | I 82; II 84; | NS | 2005 | NA | F: 0.9 | III 77; IV 73 |
| Routh | 225 pts
| 2.4 | S: 0.8 (0.4–2.0) | Univariate | I 63; II 72; III 57; | NS | 2006 | 0.8 (0.3–2.0) | F: 0.8 (0.3–1.8) | IV 14 (By patients) |
| | | 2.6 | NA | Studied
as categorical | I 100; II 83; | Lower () | Yucel | 259
| variable with cutoff
| III 73; | volume
| 2007 | | / mL using | IV
53, | significant | | | multivariable
analysis | V 29 | |
| | | 2.3 | NA | Studied
as categorical | I 83; | NS | Routh | 453
| variable with cut off | II 82; | 2007 | 0.93 (0.2–3.5) | / mL using | III 66; | | | multivariable
analysis | IV 53 |
| | | 3 | | | I 100, | Higher | Dave 2007 | 196 | S: | Studied
as continuous | II 75; | volume | (Accepted J | | F: | variable using | III 57; | significant
on | Urol) | | | multivariable analysis | IV
37; | multivariable | | | | | V 46 | analysis |
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