Effects of Angiotensin Converting Enzyme Inhibitors on Liver Fibrosis in HIV and Hepatitis C Coinfection

Table 5

Factors associated with an elevated Forns score on multivariate analysis (𝑛 = 69)*.

Variable	Beta estimate**	Standard error	P value
ACEI use for three years	1.924	0.507	<0.001
Age	0.060	0.024	0.014
Race	−1.174	0.395	0.004
HIV viral load	−5.893e^−6	0.000	0.02
Clinical evidence of cirrhosis	2.129	0.380	<0.001
Gender	0.304	0.386	0.434
BMI	−0.017	0.032	0.584
Diabetes	−0.500	0.432	0.251
Proteinuria	−0.003	0.002	0.155
HCV viral load	−2.055e^−8	0.000	0.397
HBV surface antigen positivity	−1.285	1.153	0.27
Prior treatment with interferon	0.444	0.706	0.532
Alcohol use	0.332	0.425	0.437
Marijuana use	−0.186	0.898	0.836

*The final model included ACEI use for three years, age, race, HIV viral load, clinical evidence of cirrhosis with an adjusted 𝑅² of 0.587, a standard error of the estimate of 1.498, and an overall 𝑃 value < 0.001.
**Beta estimate is the magnitude of effect that each variable has on the Forns score.