Crystal Structures of the Putative Isocitrate Dehydrogenase from Sulfolobus tokodaii Strain 7 in the Apo and NADP⁺-Bound Forms

Figure 1

Overview of structures of homodimer of ST2166. (a) Structure of the apo form. The view is along a noncrystallographic 2-fold axis, which relates the two subunits of the dimer. Polypeptide chains are shown with a cylinder model and colored rainbow from blue (N-terminus) to red (C-terminus) in A chain and light blue in B chain, respectively. (b) View of the monomer of the apo form. Polypeptide chain is shown with a ribbon model. (c) Structure of the NADP⁺-bound form. NADP⁺ molecule is drawn as a line model. Oxygen, nitrogen, and sulfur atoms are shown in purple, red, blue, and orange, respectively. (d) View of the monomer of the apo form drawn in a ribbon model.

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