Due to technological advancement in biomedical fields such as medical implants, drug delivery, biosensors, and tissue engineering, antifouling polymers have become the backbone of these research areas. The undesirable adhesion of biological compounds in numerous areas including implant materials presents a significant health risk. For example, the design of antifouling materials that resist nonspecific protein, cell, virus, and bacteria adsorption is of special interest due to its critical role in the performance of medical devices that come in contact with physiological fluids.

Polymer researchers have been working on numerous aspects in biomedical fields and bio-related applications such as antifouling. Due to their reliability, inexpensiveness, and rapidness, antifouling polymer materials have become key factors in areas related to healthcare. Antifouling polymeric material has had a key role in medical implants. Surface functionalization of implantable medical devices with polymeric antimicrobials and antifouling agents is an efficient strategy to prevent bacterial fouling and associated infections. Antifouling polymeric materials are also used as biofilms in some treatments. However, the demand for perfecting these antifouling polymer systems remains a challenge.

This Special Issue encourages all original research and review papers from a broad variety of research areas with a special emphasis on implementing polymer systems in healthcare. This Issue has been designed for the polymer and copolymers system used within the broad spectrum of healthcare and its products. Polymer-based systems, which are tested in real-world biomedical applications, are especially encouraged. New polymer systems for possible bio-applications would only be accepted if they have a comprehensive study and evaluation of the polymer system explaining the suitability of the polymer system designed for its anticipated applications.

Potential topics include but are not limited to the following:

• Technology of antifouling polymers and compositions
• Structure-property relationship in antifouling polymers
• Functional Antifouling polymeric coatings and drug delivery
• Bioinspired Antifouling Polymers
• Infection prevention by antifouling polymeric systems
• Antifouling polymeric systems for medical implants
• Antifouling polymer brushes for biomedical applications
• Antifouling polymers for tissue engineering
• Antifouling polymers in biomedical devices